7erd: Difference between revisions
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<StructureSection load='7erd' size='340' side='right'caption='[[7erd]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='7erd' size='340' side='right'caption='[[7erd]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[7erd]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ERD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ERD FirstGlance]. <br> | <table><tr><td colspan='2'>[[7erd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ERD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ERD FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=JBO:2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]pyridine-3-carboxylic+acid'>JBO</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=JBO:2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]pyridine-3-carboxylic+acid'>JBO</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7erd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7erd OCA], [https://pdbe.org/7erd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7erd RCSB], [https://www.ebi.ac.uk/pdbsum/7erd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7erd ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7erd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7erd OCA], [https://pdbe.org/7erd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7erd RCSB], [https://www.ebi.ac.uk/pdbsum/7erd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7erd ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/BLVRB_HUMAN BLVRB_HUMAN] Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to heme catabolism and metabolizes linear tetrapyrroles. Can also reduce the complexed Fe(3+) iron to Fe(2+) in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin.<ref>PMID:10620517</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 7erd" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 7erd" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Flavin reductase|Flavin reductase]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Griesinger | [[Category: Griesinger C]] | ||
[[Category: Ha | [[Category: Ha JH]] | ||
[[Category: Kim | [[Category: Kim M]] | ||
[[Category: Lee | [[Category: Lee D]] | ||
[[Category: Ryu | [[Category: Ryu KS]] | ||