7d23: Difference between revisions
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<StructureSection load='7d23' size='340' side='right'caption='[[7d23]], [[Resolution|resolution]] 1.40Å' scene=''> | <StructureSection load='7d23' size='340' side='right'caption='[[7d23]], [[Resolution|resolution]] 1.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[7d23]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[7d23]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ixodes_scapularis Ixodes scapularis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7D23 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7D23 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7d23 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7d23 OCA], [https://pdbe.org/7d23 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7d23 RCSB], [https://www.ebi.ac.uk/pdbsum/7d23 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7d23 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7d23 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7d23 OCA], [https://pdbe.org/7d23 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7d23 RCSB], [https://www.ebi.ac.uk/pdbsum/7d23 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7d23 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/QPCT_IXOSC QPCT_IXOSC] Responsible for the biosynthesis of pyroglutamyl peptides (PubMed:23770496, PubMed:24598748). Seems to have a preference for substrates with neutral or hydrophobic amino-acid residues at the second and third positions (PubMed:24598748). Shows activity towards the peptides [Gln-1]-corazonin, [Gln-1]-periviscerokinin and [Gln-1]-sulfakinin (PubMed:24598748).<ref>PMID:23770496</ref> <ref>PMID:24598748</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 7d23" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 7d23" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Glutaminyl cyclase|Glutaminyl cyclase]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Ixodes scapularis]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Hsieh | [[Category: Hsieh W-L]] | ||
[[Category: Huang | [[Category: Huang J-S]] | ||
[[Category: Huang | [[Category: Huang K-F]] | ||
[[Category: Wang | [[Category: Wang AH-J]] | ||
[[Category: Wu | [[Category: Wu M-L]] | ||