6jcu: Difference between revisions

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<StructureSection load='6jcu' size='340' side='right'caption='[[6jcu]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='6jcu' size='340' side='right'caption='[[6jcu]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6jcu]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JCU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JCU FirstGlance]. <br>
<table><tr><td colspan='2'>[[6jcu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JCU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JCU FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.297&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HIC:4-METHYL-HISTIDINE'>HIC</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=HIC:4-METHYL-HISTIDINE'>HIC</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6jbk|6jbk]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jcu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jcu OCA], [https://pdbe.org/6jcu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jcu RCSB], [https://www.ebi.ac.uk/pdbsum/6jcu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jcu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jcu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jcu OCA], [http://pdbe.org/6jcu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jcu RCSB], [http://www.ebi.ac.uk/pdbsum/6jcu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jcu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT]] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. [[http://www.uniprot.org/uniprot/COBL_MOUSE COBL_MOUSE]] Plays an important role in the reorganization of the actin cytoskeleton. Binds to and sequesters actin monomers (G actin). Nucleates actin polymerization by assembling three actin monomers in cross-filament orientation and thereby promotes growth of actin filaments at the barbed end. Can also mediate actin depolymerization at barbed ends and severing of actin filaments. Promotes formation of cell ruffles. Regulates neuron morphogenesis and increases branching of axons and dendrites. Regulates dendrite branching in Purkinje cells.<ref>PMID:17956734</ref> <ref>PMID:23223303</ref> 
[https://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
== References ==
 
<references/>
==See Also==
*[[Actin 3D structures|Actin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Robinson, R C]]
[[Category: Mus musculus]]
[[Category: Scipion, C P.M]]
[[Category: Oryctolagus cuniculus]]
[[Category: Actin]]
[[Category: Robinson RC]]
[[Category: Protein binding]]
[[Category: Scipion CPM]]
[[Category: Sequestering]]
[[Category: Structural protein-protein binding complex]]
[[Category: Wh2]]

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