6ige: Difference between revisions

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 ==Crystal structure of Human Papillomavirus type 33 pentamer==
-<StructureSection load='6ige' size='340' side='right' caption='[[6ige]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
+<StructureSection load='6ige' size='340' side='right'caption='[[6ige]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[6ige]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Hpv33 Hpv33]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IGE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IGE FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6ige]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_papillomavirus_33 Human papillomavirus 33]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IGE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IGE FirstGlance]. <br>
-</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">L1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10586 HPV33])</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ige FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ige OCA], [http://pdbe.org/6ige PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ige RCSB], [http://www.ebi.ac.uk/pdbsum/6ige PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ige ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ige FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ige OCA], [https://pdbe.org/6ige PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ige RCSB], [https://www.ebi.ac.uk/pdbsum/6ige PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ige ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/VL1_HPV33 VL1_HPV33] Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2.[HAMAP-Rule:MF_04002]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 16: / Line 18: @@
 </div>
 <div class="pdbe-citations 6ige" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Hpv33]]
+[[Category: Human papillomavirus 33]]
-[[Category: Gu, Y]]
+[[Category: Large Structures]]
-[[Category: He, M Z]]
+[[Category: Gu Y]]
-[[Category: Li, S W]]
+[[Category: He MZ]]
-[[Category: Li, Z H]]
+[[Category: Li SW]]
-[[Category: Song, S]]
+[[Category: Li ZH]]
-[[Category: Capsid protein]]
+[[Category: Song S]]
-[[Category: Structural protein]]