8ems: Difference between revisions
Jump to navigation
Jump to search
m Protected "8ems" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 4: | Line 4: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[8ems]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8EMS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8EMS FirstGlance]. <br> | <table><tr><td colspan='2'>[[8ems]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8EMS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8EMS FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.65Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ems FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ems OCA], [https://pdbe.org/8ems PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ems RCSB], [https://www.ebi.ac.uk/pdbsum/8ems PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ems ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ems FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ems OCA], [https://pdbe.org/8ems PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ems RCSB], [https://www.ebi.ac.uk/pdbsum/8ems PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ems ProSAT]</span></td></tr> | ||
</table> | </table> | ||
Latest revision as of 14:33, 15 November 2023
Cryo-EM structure of human liver glycogen phosphorylaseCryo-EM structure of human liver glycogen phosphorylase
Structural highlights
DiseasePYGL_HUMAN Defects in PYGL are the cause of glycogen storage disease type 6 (GSD6) [MIM:232700. A metabolic disorder characterized by mild to moderate hypoglycemia, mild ketosis, growth retardation, and prominent hepatomegaly. Heart and skeletal muscle are not affected.[1] FunctionPYGL_HUMAN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. References |
| ||||||||||||||||||