6dw1: Difference between revisions

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 <SX load='6dw1' size='340' side='right' viewer='molstar' caption='[[6dw1]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[6dw1]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DW1 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6DW1 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6dw1]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DW1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DW1 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ABU:GAMMA-AMINO-BUTANOIC+ACID'>ABU</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6dw0|6dw0]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ABU:GAMMA-AMINO-BUTANOIC+ACID'>ABU</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Gabrg2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat]), Gabra1, Gabra-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat]), Gabrb1, Gabrb-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6dw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dw1 OCA], [https://pdbe.org/6dw1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6dw1 RCSB], [https://www.ebi.ac.uk/pdbsum/6dw1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6dw1 ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6dw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dw1 OCA], [http://pdbe.org/6dw1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dw1 RCSB], [http://www.ebi.ac.uk/pdbsum/6dw1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dw1 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/GBRG2_RAT GBRG2_RAT]] GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. [[http://www.uniprot.org/uniprot/GBRB1_RAT GBRB1_RAT]] Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.<ref>PMID:18281286</ref> <ref>PMID:1977069</ref>  [[http://www.uniprot.org/uniprot/GBRA1_RAT GBRA1_RAT]] Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.<ref>PMID:1376242</ref> <ref>PMID:18281286</ref> <ref>PMID:2540033</ref>
+[https://www.uniprot.org/uniprot/GBRG2_RAT GBRG2_RAT] GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
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 __TOC__
 </SX>
-[[Category: Buffalo rat]]
 [[Category: Large Structures]]
-[[Category: Gouaux, E]]
+[[Category: Rattus norvegicus]]
-[[Category: Phulera, S]]
+[[Category: Gouaux E]]
-[[Category: Yoshioka, C]]
+[[Category: Phulera S]]
-[[Category: Yu, J]]
+[[Category: Yoshioka C]]
-[[Category: Zhu, H]]
+[[Category: Yu J]]
-[[Category: Cys loop receptor]]
+[[Category: Zhu H]]
-[[Category: Gaba]]
-[[Category: Gaba receptor]]
-[[Category: Ion channel]]
-[[Category: Membrane protein]]
-[[Category: Neurotransmission]]