3lap: Difference between revisions

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==The Structure of the Intermediate Complex of the Arginine Repressor from Mycobacterium tuberculosis Bound to its DNA Operator and L-canavanine.==
==The Structure of the Intermediate Complex of the Arginine Repressor from Mycobacterium tuberculosis Bound to its DNA Operator and L-canavanine.==
<StructureSection load='3lap' size='340' side='right' caption='[[3lap]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
<StructureSection load='3lap' size='340' side='right'caption='[[3lap]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3lap]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LAP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LAP FirstGlance]. <br>
<table><tr><td colspan='2'>[[3lap]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LAP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LAP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GGB:L-CANAVANINE'>GGB</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3bue|3bue]], [[2zfz|2zfz]], [[3cag|3cag]], [[3ere|3ere]], [[3fhz|3fhz]], [[3laj|3laj]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GGB:L-CANAVANINE'>GGB</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ahrC, argR, MT1695, MTCY06H11.22, Rv1657 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lap OCA], [https://pdbe.org/3lap PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lap RCSB], [https://www.ebi.ac.uk/pdbsum/3lap PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lap ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lap OCA], [http://pdbe.org/3lap PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3lap RCSB], [http://www.ebi.ac.uk/pdbsum/3lap PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3lap ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ARGR_MYCTU ARGR_MYCTU]] Regulates arginine biosynthesis genes (By similarity).  
[https://www.uniprot.org/uniprot/ARGR_MYCTU ARGR_MYCTU] Regulates arginine biosynthesis genes (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Arginine repressor|Arginine repressor]]
*[[Arginine repressor 3D structures|Arginine repressor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Myctu]]
[[Category: Large Structures]]
[[Category: Cherney, L T]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Cherney, M M]]
[[Category: Cherney LT]]
[[Category: Garen, C R]]
[[Category: Cherney MM]]
[[Category: James, M N.G]]
[[Category: Garen CR]]
[[Category: Structural genomic]]
[[Category: James MNG]]
[[Category: Amino-acid biosynthesis]]
[[Category: Arginine biosynthesis]]
[[Category: Arginine repressor]]
[[Category: Argr-dna-canavanine ternary complex]]
[[Category: Cytoplasm]]
[[Category: Dna binding]]
[[Category: Dna-binding]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis structural proteomics project]]
[[Category: Repressor]]
[[Category: Tbsgc]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transcription regulator]]
[[Category: Transcription regulator-dna complex]]
[[Category: Xmtb]]

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