5n53: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
 ==Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with N-(3-chloro-4-methoxyphenyl) acetamide==
-<StructureSection load='5n53' size='340' side='right' caption='[[5n53]], [[Resolution|resolution]] 1.48&Aring;' scene=''>
+<StructureSection load='5n53' size='340' side='right'caption='[[5n53]], [[Resolution|resolution]] 1.48&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[5n53]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N53 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5N53 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[5n53]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N53 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5N53 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8NB:~{N}-(3-CHLORANYL-4-METHOXY-PHENYL)ETHANAMIDE'>8NB</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.48&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PHGDH, PGDH3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8NB:~{N}-(3-CHLORANYL-4-METHOXY-PHENYL)ETHANAMIDE'>8NB</scene></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoglycerate_dehydrogenase Phosphoglycerate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.95 1.1.1.95] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5n53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n53 OCA], [https://pdbe.org/5n53 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5n53 RCSB], [https://www.ebi.ac.uk/pdbsum/5n53 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5n53 ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5n53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n53 OCA], [http://pdbe.org/5n53 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5n53 RCSB], [http://www.ebi.ac.uk/pdbsum/5n53 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5n53 ProSAT]</span></td></tr>
 </table>
 == Disease ==
-[[http://www.uniprot.org/uniprot/SERA_HUMAN SERA_HUMAN]] Defects in PHGDH are the cause of phosphoglycerate dehydrogenase deficiency (PHGDH deficiency) [MIM:[http://omim.org/entry/601815 601815]]. It is characterized by congenital microcephaly, psychomotor retardation, and seizures.
+[https://www.uniprot.org/uniprot/SERA_HUMAN SERA_HUMAN] Defects in PHGDH are the cause of phosphoglycerate dehydrogenase deficiency (PHGDH deficiency) [MIM:[https://omim.org/entry/601815 601815]. It is characterized by congenital microcephaly, psychomotor retardation, and seizures.
+== Function ==
+[https://www.uniprot.org/uniprot/SERA_HUMAN SERA_HUMAN]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 27: / Line 28: @@
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
-[[Category: Phosphoglycerate dehydrogenase]]
+[[Category: Large Structures]]
-[[Category: Basle, A]]
+[[Category: Basle A]]
-[[Category: Blackburn, T J]]
+[[Category: Blackburn TJ]]
-[[Category: Cano, C]]
+[[Category: Cano C]]
-[[Category: Curtin, N J]]
+[[Category: Curtin NJ]]
-[[Category: Noble, M E.M]]
+[[Category: Noble MEM]]
-[[Category: Tucker, J]]
+[[Category: Tucker J]]
-[[Category: Unterlass, J E]]
+[[Category: Unterlass JE]]
-[[Category: Dehydrogenase]]
-[[Category: Fbdd]]
-[[Category: Oxidoreductase]]
-[[Category: Serine metabolism]]