5msc: Difference between revisions

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<StructureSection load='5msc' size='340' side='right'caption='[[5msc]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='5msc' size='340' side='right'caption='[[5msc]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5msc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dsm_45197 Dsm 45197]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MSC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MSC FirstGlance]. <br>
<table><tr><td colspan='2'>[[5msc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Nocardia_iowensis Nocardia iowensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MSC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MSC FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">car ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=204891 DSM 45197])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5msc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5msc OCA], [http://pdbe.org/5msc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5msc RCSB], [http://www.ebi.ac.uk/pdbsum/5msc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5msc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5msc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5msc OCA], [https://pdbe.org/5msc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5msc RCSB], [https://www.ebi.ac.uk/pdbsum/5msc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5msc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CAR_NOCIO CAR_NOCIO]] Catalyzes the reduction of a very wide range of aliphatic carboxylic acids as well as many aryl carboxylic acids into their corresponding aldehydes, by using ATP for energy to drive the reaction. Aryl carboxylic acid substrates include substituted benzoic acids, phenyl-substituted aliphatic acids, heterocyclic carboxylic acids, and polyaromatic ring carboxylic acids. Cannot reduce benzaldehyde to benzyl alcohol.<ref>PMID:15006821</ref> <ref>PMID:17102130</ref> <ref>PMID:9171390</ref> <ref>PMID:9171390</ref>
[https://www.uniprot.org/uniprot/CAR_NOCIO CAR_NOCIO] Catalyzes the reduction of a very wide range of aliphatic carboxylic acids as well as many aryl carboxylic acids into their corresponding aldehydes, by using ATP for energy to drive the reaction. Aryl carboxylic acid substrates include substituted benzoic acids, phenyl-substituted aliphatic acids, heterocyclic carboxylic acids, and polyaromatic ring carboxylic acids. Cannot reduce benzaldehyde to benzyl alcohol.<ref>PMID:15006821</ref> <ref>PMID:17102130</ref> <ref>PMID:9171390</ref> <ref>PMID:9171390</ref>  
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Dsm 45197]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Dunstan, M S]]
[[Category: Nocardia iowensis]]
[[Category: Leys, D]]
[[Category: Dunstan MS]]
[[Category: Adenylation domain]]
[[Category: Leys D]]
[[Category: Carboxylic acid reductase]]
[[Category: Oxidoreductase]]

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