3vpn: Difference between revisions

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<StructureSection load='3vpn' size='340' side='right'caption='[[3vpn]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
<StructureSection load='3vpn' size='340' side='right'caption='[[3vpn]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3vpn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VPN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VPN FirstGlance]. <br>
<table><tr><td colspan='2'>[[3vpn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VPN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VPN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3olj|3olj]], [[3vpm|3vpm]], [[3vpo|3vpo]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RR2, RRM2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vpn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vpn OCA], [https://pdbe.org/3vpn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vpn RCSB], [https://www.ebi.ac.uk/pdbsum/3vpn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vpn ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vpn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vpn OCA], [https://pdbe.org/3vpn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vpn RCSB], [https://www.ebi.ac.uk/pdbsum/3vpn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vpn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/RIR2_HUMAN RIR2_HUMAN]] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.  
[https://www.uniprot.org/uniprot/RIR2_HUMAN RIR2_HUMAN] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.


==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Ribonucleoside-diphosphate reductase]]
[[Category: Chen B]]
[[Category: Chen, B]]
[[Category: Chen X]]
[[Category: Chen, X]]
[[Category: Liu H]]
[[Category: Liu, H]]
[[Category: Shao J]]
[[Category: Shao, J]]
[[Category: Xu Z]]
[[Category: Xu, Z]]
[[Category: Yang C]]
[[Category: Yang, C]]
[[Category: Zhang L]]
[[Category: Zhang, L]]
[[Category: Zhu L]]
[[Category: Zhu, L]]
[[Category: Zhu W]]
[[Category: Zhu, W]]
[[Category: Metal-binding]]
[[Category: Oxidoreductase]]

Latest revision as of 15:31, 8 November 2023

Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutantCrystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant

Structural highlights

3vpn is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.25Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RIR2_HUMAN Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.

See Also

3vpn, resolution 2.25Å

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