5ml3: Difference between revisions

<table><tr><td colspan='2'>[[5ml3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ML3 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5ML3 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DL3:~{N}1-[(4-CHLOROPHENYL)METHYL]-~{N}1-CYCLOPENTYL-~{N}4-[[2-(METHYLAMINO)PYRIMIDIN-4-YL]METHYL]-~{N}4-(PIPERIDIN-4-YLMETHYL)BENZENE-1,4-DISULFONAMIDE'>DL3</scene></td></tr>

<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDE6D, PDED ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ml3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ml3 OCA], [http://pdbe.org/5ml3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ml3 RCSB], [http://www.ebi.ac.uk/pdbsum/5ml3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ml3 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/PDE6D_HUMAN PDE6D_HUMAN]] Acts as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude and does so by decreasing the nucleotide dissociation rate. Stabilizes Arl3-GTP by decreasing the nucleotide dissociation (By similarity).  

[[Category: Human]]

[[Category: Fansa, E K]]

[[Category: Martin-Gago, P]]

[[Category: Waldmann, H]]

[[Category: Wittinghofer, A]]

[[Category: Prenyl binding protein]]