3iwk: Difference between revisions

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 <StructureSection load='3iwk' size='340' side='right'caption='[[3iwk]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3iwk]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Garden_pea Garden pea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IWK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IWK FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3iwk]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Pisum_sativum Pisum sativum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IWK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IWK FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3iwj|3iwj]]</div></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">amadh1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3888 Garden pea])</td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Aminobutyraldehyde_dehydrogenase Aminobutyraldehyde dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.19 1.2.1.19] </span></td></tr>
 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iwk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iwk OCA], [https://pdbe.org/3iwk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iwk RCSB], [https://www.ebi.ac.uk/pdbsum/3iwk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iwk ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/AADH1_PEA AADH1_PEA] Dehydrogenase that catalyzes the oxidation of several aminoaldehydes (PubMed:20026072). Metabolizes and detoxifies aldehyde products of polyamine degradation to non-toxic amino acids (Probable). Catalyzes the oxidation of 3-aminopropanal to beta-alanine (Ref.1, PubMed:20026072). Catalyzes the oxidation of 4-aminobutanal to 4-aminobutanoate (PubMed:20026072). Catalyzes the oxidation of 4-guanidinobutanal to 4-guanidinobutanoate (PubMed:20026072).<ref>PMID:20026072</ref> [UniProtKB:P20000]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
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 __TOC__
 </StructureSection>
-[[Category: Aminobutyraldehyde dehydrogenase]]
-[[Category: Garden pea]]
 [[Category: Large Structures]]
-[[Category: Briozzo, P]]
+[[Category: Pisum sativum]]
-[[Category: Kopecny, D]]
+[[Category: Briozzo P]]
-[[Category: Morera, S]]
+[[Category: Kopecny D]]
-[[Category: Aminoaldehyde dehydrogenase]]
+[[Category: Morera S]]
-[[Category: Betaine aldehyde dehydrogenase]]
-[[Category: Dimer]]
-[[Category: Nad]]
-[[Category: Oxidoreductase]]
-[[Category: Rossmann fold]]