3h4t: Difference between revisions
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<StructureSection load='3h4t' size='340' side='right'caption='[[3h4t]], [[Resolution|resolution]] 1.15Å' scene=''> | <StructureSection load='3h4t' size='340' side='right'caption='[[3h4t]], [[Resolution|resolution]] 1.15Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3h4t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[3h4t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Actinoplanes_teichomyceticus Actinoplanes teichomyceticus] and [https://en.wikipedia.org/wiki/Amycolatopsis_orientalis Amycolatopsis orientalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H4T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3H4T FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.15Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h4t OCA], [https://pdbe.org/3h4t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h4t RCSB], [https://www.ebi.ac.uk/pdbsum/3h4t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h4t ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h4t OCA], [https://pdbe.org/3h4t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h4t RCSB], [https://www.ebi.ac.uk/pdbsum/3h4t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h4t ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/GTFA_AMYOR GTFA_AMYOR] Catalyzes the attachment of 4-epi-vancosamine from a TDP donor to the beta-OH-Tyr-6 of the aglycone cosubstrate in the biosynthesis of glycopeptide antibiotic chloroeremomycin, a member of the vancomycin group of antibiotics. Strongly prefers devancoaminyl-vancomycin (DVV) as substrate rather than the heptapeptide vancomycin aglycone (AGV). Acts downstream of GtfB.<ref>PMID:15070728</ref> <ref>PMID:19549605</ref> <ref>PMID:9115410</ref> [https://www.uniprot.org/uniprot/Q6ZZJ7_ACTTI Q6ZZJ7_ACTTI] | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Actinoplanes teichomyceticus | [[Category: Actinoplanes teichomyceticus]] | ||
[[Category: Amycolatopsis orientalis]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Blundell | [[Category: Blundell TL]] | ||
[[Category: Dias | [[Category: Dias MVB]] | ||
[[Category: Huang | [[Category: Huang F]] | ||
[[Category: Spencer | [[Category: Spencer JB]] | ||
[[Category: Truman | [[Category: Truman AW]] | ||
[[Category: Wu | [[Category: Wu S]] | ||