2e9z: Difference between revisions
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<StructureSection load='2e9z' size='340' side='right'caption='[[2e9z]], [[Resolution|resolution]] 3.00Å' scene=''> | <StructureSection load='2e9z' size='340' side='right'caption='[[2e9z]], [[Resolution|resolution]] 3.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2e9z]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Foot-and- | <table><tr><td colspan='2'>[[2e9z]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Foot-and-mouth_disease_virus_C-S8c1 Foot-and-mouth disease virus C-S8c1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E9Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E9Z FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene>, <scene name='pdbligand=UTP:URIDINE+5-TRIPHOSPHATE'>UTP</scene></td></tr> | |||
<tr id=' | |||
< | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e9z OCA], [https://pdbe.org/2e9z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e9z RCSB], [https://www.ebi.ac.uk/pdbsum/2e9z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e9z ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e9z OCA], [https://pdbe.org/2e9z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e9z RCSB], [https://www.ebi.ac.uk/pdbsum/2e9z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e9z ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/Q9QCE4_9PICO Q9QCE4_9PICO] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266] RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047] | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Foot-and-mouth disease virus | [[Category: Foot-and-mouth disease virus C-S8c1]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Arias A]] | |||
[[Category: Arias | [[Category: Domingo E]] | ||
[[Category: Domingo | [[Category: Escarmis C]] | ||
[[Category: Escarmis | [[Category: Ferrer-Orta C]] | ||
[[Category: Ferrer-Orta | [[Category: Perez-Luque R]] | ||
[[Category: Perez-Luque | [[Category: Verdaguer N]] | ||
[[Category: Verdaguer | |||