1nrx: Difference between revisions

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<StructureSection load='1nrx' size='340' side='right'caption='[[1nrx]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='1nrx' size='340' side='right'caption='[[1nrx]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1nrx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/A._nidulans A. nidulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NRX OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1NRX FirstGlance]. <br>
<table><tr><td colspan='2'>[[1nrx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_nidulans Aspergillus nidulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NRX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NRX FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1nr5|1nr5]], [[1nve|1nve]], [[1nvd|1nvd]], [[1nvb|1nvb]], [[1nua|1nua]], [[1nva|1nva]], [[1nvf|1nvf]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AROMA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=162425 A. nidulans])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nrx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nrx OCA], [https://pdbe.org/1nrx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nrx RCSB], [https://www.ebi.ac.uk/pdbsum/1nrx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nrx ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_synthase 3-dehydroquinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.4 4.2.3.4] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1nrx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nrx OCA], [http://pdbe.org/1nrx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nrx RCSB], [http://www.ebi.ac.uk/pdbsum/1nrx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1nrx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ARO1_EMENI ARO1_EMENI]] The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.[HAMAP-Rule:MF_03143]  
[https://www.uniprot.org/uniprot/ARO1_EMENI ARO1_EMENI] The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.[HAMAP-Rule:MF_03143]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: 3-dehydroquinate synthase]]
[[Category: Aspergillus nidulans]]
[[Category: A. nidulans]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Hawkins, A R]]
[[Category: Hawkins AR]]
[[Category: Lamb, H K]]
[[Category: Lamb HK]]
[[Category: Nichols, C E]]
[[Category: Nichols CE]]
[[Category: Ren, J]]
[[Category: Ren J]]
[[Category: Stammers, D K]]
[[Category: Stammers DK]]
[[Category: Aromatic amino acid biosynthesis]]
[[Category: Closed form]]
[[Category: Cyclase]]
[[Category: Dhq]]
[[Category: Domain movement]]
[[Category: Form f]]
[[Category: Lyase]]
[[Category: Shikimate pathway]]

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