7n2x: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[7n2x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_O157:H7 Escherichia coli O157:H7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7N2X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7N2X FirstGlance]. <br> | <table><tr><td colspan='2'>[[7n2x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_O157:H7 Escherichia coli O157:H7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7N2X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7N2X FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DHA:2-AMINO-ACRYLIC+ACID'>DHA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=P4G:1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE'>P4G</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DHA:2-AMINO-ACRYLIC+ACID'>DHA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=P4G:1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE'>P4G</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7n2x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7n2x OCA], [https://pdbe.org/7n2x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7n2x RCSB], [https://www.ebi.ac.uk/pdbsum/7n2x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7n2x ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7n2x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7n2x OCA], [https://pdbe.org/7n2x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7n2x RCSB], [https://www.ebi.ac.uk/pdbsum/7n2x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7n2x ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/AZOR_ECO57 AZOR_ECO57] Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.[HAMAP-Rule:MF_01216] Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.[HAMAP-Rule:MF_01216] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Latest revision as of 19:23, 18 October 2023
The crystal structure of an FMN-dependent NADH:quinone oxidoreductase, AzoR from Escherichia coliThe crystal structure of an FMN-dependent NADH:quinone oxidoreductase, AzoR from Escherichia coli
Structural highlights
FunctionAZOR_ECO57 Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.[HAMAP-Rule:MF_01216] Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.[HAMAP-Rule:MF_01216] |
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