7lip: Difference between revisions
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<StructureSection load='7lip' size='340' side='right'caption='[[7lip]], [[Resolution|resolution]] 1.48Å' scene=''> | <StructureSection load='7lip' size='340' side='right'caption='[[7lip]], [[Resolution|resolution]] 1.48Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[7lip]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[7lip]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LIP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LIP FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.48Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lip FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lip OCA], [https://pdbe.org/7lip PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lip RCSB], [https://www.ebi.ac.uk/pdbsum/7lip PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lip ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lip FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lip OCA], [https://pdbe.org/7lip PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lip RCSB], [https://www.ebi.ac.uk/pdbsum/7lip PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lip ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/SPOP_HUMAN SPOP_HUMAN] Inhibits IPF1/PDX1 transactivation of established target promoters, such as insulin, may be by recruiting a repressor complex (By similarity). In complex with CUL3, involved in ubiquitination of BMI1, H2AFY and DAXX, and probably also in ubiquitination and proteasomal degradation of Gli2 or Gli3.<ref>PMID:14528312</ref> <ref>PMID:15897469</ref> <ref>PMID:16524876</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 7lip" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 7lip" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Speckle-type POZ protein 3D structures|Speckle-type POZ protein 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Botuyan | [[Category: Botuyan MV]] | ||
[[Category: Cui | [[Category: Cui G]] | ||
[[Category: Mer | [[Category: Mer G]] | ||