1nik: Difference between revisions

Revision as of 02:34, 3 May 2008

Wild Type RNA Polymerase II

OverviewOverview

The x-ray structure of complete RNA polymerase II from Saccharomyces cerevisiae has been determined, including a heterodimer of subunits Rpb4 and Rpb7 not present in previous "core" polymerase II structures. The heterodimer maintains the polymerase in the conformation of a transcribing complex, may bind RNA as it emerges from the enzyme, and is in a position to interact with general transcription factors and the Mediator of transcriptional regulation.

About this StructureAbout this Structure

1NIK is a Protein complex structure of sequences from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

ReferenceReference

Complete, 12-subunit RNA polymerase II at 4.1-A resolution: implications for the initiation of transcription., Bushnell DA, Kornberg RD, Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):6969-73. Epub 2003 May 13. PMID:12746498 Page seeded by OCA on Sat May 3 02:34:39 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
 [[Image:1nik.gif|left|200px]]
- {{Structure
+<!--
-|PDB= 1nik |SIZE=350|CAPTION= <scene name='initialview01'>1nik</scene>, resolution 4.10&Aring;
+The line below this paragraph, containing "STRUCTURE_1nik", creates the "Structure Box" on the page.
-|SITE=
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
-|LIGAND= <scene name='pdbligand=UNK:UNKNOWN'>UNK</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span>
+or leave the SCENE parameter empty for the default display.
-|GENE=
+-->
-|DOMAIN=
+{{STRUCTURE_1nik|  PDB=1nik  |  SCENE=  }}
-|RELATEDENTRY=
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nik FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nik OCA], [http://www.ebi.ac.uk/pdbsum/1nik PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1nik RCSB]</span>
-}}
 '''Wild Type RNA Polymerase II'''
@@ Line 28: / Line 25: @@
 [[Category: Bushnell, D A.]]
 [[Category: Kornberg, R D.]]
-[[Category: transferase]]
+[[Category: Transferase]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 02:34:39 2008''
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:30:51 2008''