6uui: Difference between revisions
No edit summary |
No edit summary |
||
Line 3: | Line 3: | ||
<StructureSection load='6uui' size='340' side='right'caption='[[6uui]], [[Resolution|resolution]] 2.07Å' scene=''> | <StructureSection load='6uui' size='340' side='right'caption='[[6uui]], [[Resolution|resolution]] 2.07Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6uui]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[6uui]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UUI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6UUI FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.069Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6uui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6uui OCA], [https://pdbe.org/6uui PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6uui RCSB], [https://www.ebi.ac.uk/pdbsum/6uui PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6uui ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Disease == | == Disease == | ||
[ | [https://www.uniprot.org/uniprot/K2C1_HUMAN K2C1_HUMAN] Epidermolytic palmoplantar keratoderma;Ichthyosis hystrix of Curth-Macklin;Annular epidermolytic ichthyosis;Epidermolytic ichthyosis;Keratosis palmoplantaris striata. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/K2C1_HUMAN K2C1_HUMAN] May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK.<ref>PMID:17956333</ref> <ref>PMID:21544310</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Line 22: | Line 21: | ||
</div> | </div> | ||
<div class="pdbe-citations 6uui" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 6uui" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Keratins|Keratins]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Bunick | [[Category: Bunick CG]] | ||
[[Category: Lomakin | [[Category: Lomakin IB]] | ||