6pel: Difference between revisions

Revision as of 10:27, 11 October 2023

Crystal structure of bovine opsin with citronellol boundCrystal structure of bovine opsin with citronellol bound

Structural highlights

6pel is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 3.186Å
Ligands:	, , , ,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

OPSD_BOVIN Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal (By similarity).^[1] ^[2]

References

↑ Nakamichi H, Okada T. Local peptide movement in the photoreaction intermediate of rhodopsin. Proc Natl Acad Sci U S A. 2006 Aug 22;103(34):12729-34. Epub 2006 Aug 14. PMID:16908857
↑ Salom D, Lodowski DT, Stenkamp RE, Le Trong I, Golczak M, Jastrzebska B, Harris T, Ballesteros JA, Palczewski K. Crystal structure of a photoactivated deprotonated intermediate of rhodopsin. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16123-8. Epub 2006 Oct 23. PMID:17060607

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OCA

[1] Nakamichi H, Okada T. Local peptide movement in the photoreaction intermediate of rhodopsin. Proc Natl Acad Sci U S A. 2006 Aug 22;103(34):12729-34. Epub 2006 Aug 14. PMID:16908857

[2] Salom D, Lodowski DT, Stenkamp RE, Le Trong I, Golczak M, Jastrzebska B, Harris T, Ballesteros JA, Palczewski K. Crystal structure of a photoactivated deprotonated intermediate of rhodopsin. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16123-8. Epub 2006 Oct 23. PMID:17060607

[1]

[2]

@@ Line 1: / Line 1: @@
 ==Crystal structure of bovine opsin with citronellol bound==
-<StructureSection load='6pel' size='340' side='right'caption='[[6pel]]' scene=''>
+<StructureSection load='6pel' size='340' side='right'caption='[[6pel]], [[Resolution|resolution]] 3.19&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PEL OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6PEL FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6pel]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PEL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PEL FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6pel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pel OCA], [http://pdbe.org/6pel PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pel RCSB], [http://www.ebi.ac.uk/pdbsum/6pel PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pel ProSAT]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.186&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ODM:(3R)-3,7-dimethyloct-6-en-1-ol'>ODM</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pel OCA], [https://pdbe.org/6pel PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pel RCSB], [https://www.ebi.ac.uk/pdbsum/6pel PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pel ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/OPSD_BOVIN OPSD_BOVIN] Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal (By similarity).<ref>PMID:16908857</ref> <ref>PMID:17060607</ref>
+==See Also==
+*[[Rhodopsin 3D structures|Rhodopsin 3D structures]]
+== References ==
+<references/>
 __TOC__
 </StructureSection>
+[[Category: Bos taurus]]
 [[Category: Large Structures]]
 [[Category: Eger BT]]
 [[Category: Ernst OP]]
 [[Category: Morizumi T]]

6pel: Difference between revisions

Revision as of 10:27, 11 October 2023

Crystal structure of bovine opsin with citronellol boundCrystal structure of bovine opsin with citronellol bound

Structural highlights

Function

See Also

References

Contents

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6pel: Difference between revisions

Revision as of 10:27, 11 October 2023

Crystal structure of bovine opsin with citronellol boundCrystal structure of bovine opsin with citronellol bound

Structural highlights

Function

See Also

References

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Navigation menu

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