6pbd: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 3: / Line 3: @@
 <StructureSection load='6pbd' size='340' side='right'caption='[[6pbd]], [[Resolution|resolution]] 2.34&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[6pbd]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_15252_[[caulobacter_crescentus_poindexter_1964]] Atcc 15252 [[caulobacter crescentus poindexter 1964]]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PBD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PBD FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6pbd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Caulobacter_vibrioides Caulobacter vibrioides] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PBD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PBD FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SFG:SINEFUNGIN'>SFG</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.343&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ccrMIM, ccrM, CC_0378 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=155892 ATCC 15252 [[Caulobacter crescentus Poindexter 1964]]])</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SFG:SINEFUNGIN'>SFG</scene></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Site-specific_DNA-methyltransferase_(adenine-specific) Site-specific DNA-methyltransferase (adenine-specific)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.72 2.1.1.72] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pbd OCA], [https://pdbe.org/6pbd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pbd RCSB], [https://www.ebi.ac.uk/pdbsum/6pbd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pbd ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pbd OCA], [http://pdbe.org/6pbd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pbd RCSB], [http://www.ebi.ac.uk/pdbsum/6pbd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pbd ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/MTC1_CAUVC MTC1_CAUVC]] This methylase recognizes the double-stranded sequence GANTC and causes specific methylation on A-2 on both strands. Ccrm-mediated methylation has important cellular functions. Appears to contribute to the accurate cell-cycle control of DNA replication and cellular morphology.
+[https://www.uniprot.org/uniprot/CCRM_CAUVC CCRM_CAUVC] A beta subtype methylase that recognizes the double-stranded sequence 5'-GANTC-3' and methylates non-modifed A-2 on the hemimethylated, post-replicative DNA (Probable) (PubMed:12654995) (By similarity). Opens a bubble in the DNA at the recognition site, allowing precise recognition of the sequence and ensuring enzyme specificity (PubMed:31601797). Functions only in the predivisional cell. Responsible for 5'-GANTC-3' methylation in the cell; methylation of hemimethylated sites generated after replication fork passage occurs late in the predivisional cell, near completion of chromosome replication but prior to cell division. Contributes to the accurate cell-cycle control of DNA replication and cellular morphology (By similarity).[UniProtKB:B8GZ33]<ref>PMID:31601797</ref> <ref>PMID:12654995</ref> <ref>PMID:31601797</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 24: / Line 23: @@
 __TOC__
 </StructureSection>
+[[Category: Caulobacter vibrioides]]
 [[Category: Large Structures]]
-[[Category: Cheng, X]]
+[[Category: Synthetic construct]]
-[[Category: Horton, J R]]
+[[Category: Cheng X]]
-[[Category: Woodcock, C B]]
+[[Category: Horton JR]]
-[[Category: Base flipping]]
+[[Category: Woodcock CB]]
-[[Category: Dna methylation]]
-[[Category: Gantc recognition]]
-[[Category: Transferase-dna complex]]