6eco: Difference between revisions

<table><tr><td colspan='2'>[[6eco]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ECO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ECO FirstGlance]. <br>

</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6eco FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6eco OCA], [http://pdbe.org/6eco PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6eco RCSB], [http://www.ebi.ac.uk/pdbsum/6eco PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6eco ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/GAG_HV1H2 GAG_HV1H2]] Matrix protein p17 targets Gag and Gag-Pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus. Also mediates nuclear localization of the preintegration complex. Implicated in the release from host cell mediated by Vpu.  Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex.  Nucleocapsid protein p7 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers.  p6-gag plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1 (By similarity).  

[[Category: Summers, B J]]

[[Category: Xiong, Y]]

[[Category: Viral protein]]