5l5k: Difference between revisions
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==Plexin A4 full extracellular region, domains 1 to 10, data to 7.5 angstrom, spacegroup P4(1)== | ==Plexin A4 full extracellular region, domains 1 to 10, data to 7.5 angstrom, spacegroup P4(1)== | ||
<StructureSection load='5l5k' size='340' side='right' caption='[[5l5k]], [[Resolution|resolution]] 7.50Å' scene=''> | <StructureSection load='5l5k' size='340' side='right'caption='[[5l5k]], [[Resolution|resolution]] 7.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5l5k]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5l5k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L5K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5L5K FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 7.501Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5l5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l5k OCA], [https://pdbe.org/5l5k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5l5k RCSB], [https://www.ebi.ac.uk/pdbsum/5l5k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5l5k ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/PLXA4_MOUSE PLXA4_MOUSE] Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.<ref>PMID:12591607</ref> <ref>PMID:18262512</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
*[[Plexin|Plexin]] | *[[Plexin 3D structures|Plexin 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Coles | [[Category: Mus musculus]] | ||
[[Category: Gilbert | [[Category: Coles CH]] | ||
[[Category: Janssen | [[Category: Gilbert RJC]] | ||
[[Category: Jones | [[Category: Janssen BJC]] | ||
[[Category: Kaufmann | [[Category: Jones EY]] | ||
[[Category: Kong | [[Category: Kaufmann R]] | ||
[[Category: Malinauskas | [[Category: Kong Y]] | ||
[[Category: Ni | [[Category: Malinauskas T]] | ||
[[Category: Padilla-Parra | [[Category: Ni T]] | ||
[[Category: Pasterkamp | [[Category: Padilla-Parra S]] | ||
[[Category: Vangoor | [[Category: Pasterkamp RJ]] | ||
[[Category: Vangoor VR]] | |||