3alw: Difference between revisions

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 <StructureSection load='3alw' size='340' side='right'caption='[[3alw]], [[Resolution|resolution]] 3.55&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3alw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cotton-top_tamarin Cotton-top tamarin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ALW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ALW FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3alw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Measles_morbillivirus Measles morbillivirus], [https://en.wikipedia.org/wiki/Saguinus_oedipus Saguinus oedipus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ALW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ALW FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.55&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3alz|3alz]], [[3alx|3alx]]</div></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Hemagglutinin, CD150 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9490 Cotton-top tamarin])</td></tr>
 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3alw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3alw OCA], [https://pdbe.org/3alw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3alw RCSB], [https://www.ebi.ac.uk/pdbsum/3alw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3alw ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/HEMA_MEASE HEMA_MEASE] Attaches the virus to cell receptors and thereby initiating infection. Binding of H protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion. May use human CD46 and/or SLAMF1 as receptors for viral entry into the cell. The high degree of interaction between H and MCP/CD46 results in down-regulation of the latter from the surface of infected cells, rendering them more sensitive to c3b-mediated complement lysis.<ref>PMID:9811778</ref> [https://www.uniprot.org/uniprot/Q9GJT3_SAGOE Q9GJT3_SAGOE]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 25: / Line 26: @@
 __TOC__
 </StructureSection>
-[[Category: Cotton-top tamarin]]
 [[Category: Large Structures]]
-[[Category: Hashiguchi, T]]
+[[Category: Measles morbillivirus]]
-[[Category: Kamishikiryo, J]]
+[[Category: Saguinus oedipus]]
-[[Category: Kubota, M]]
+[[Category: Synthetic construct]]
-[[Category: Maenaka, K]]
+[[Category: Hashiguchi T]]
-[[Category: Maita, N]]
+[[Category: Kamishikiryo J]]
-[[Category: Ose, T]]
+[[Category: Kubota M]]
-[[Category: Yanagi, Y]]
+[[Category: Maenaka K]]
-[[Category: Beta-sandwich]]
+[[Category: Maita N]]
-[[Category: Immunoglobulin fold]]
+[[Category: Ose T]]
-[[Category: Six-bladed beta-propeller fold]]
+[[Category: Yanagi Y]]
-[[Category: Viral protein-membrane protein complex]]
-[[Category: Viral protein-receptor complex]]