6bon: Difference between revisions

<table><tr><td colspan='2'>[[6bon]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_fumigatus_A1163 Aspergillus fumigatus A1163]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BON OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BON FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=OAA:OXALOACETATE+ION'>OAA</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bon FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bon OCA], [https://pdbe.org/6bon PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bon RCSB], [https://www.ebi.ac.uk/pdbsum/6bon PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bon ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/PRPC_ASPFC PRPC_ASPFC] Component of the methylcitrate cycle that catalyzes the synthesis of (2S,3S)-2-methylcitrate from propionyl-CoA and oxaloacetate. Plays an important role in detoxification of propionyl-CoA, an inhibitor of both primary and secondary metabolism. Has also citrate synthase activity using as substrates acetyl-CoA and oxaloacetate. Plays a key role in the estabishment of invasive pulmonary aspergillosis.<ref>PMID:17973657</ref>  

[[Category: Aspergillus fumigatus A1163]]

[[Category: Chruszcz M]]

[[Category: Schlachter C]]