6ay1: Difference between revisions
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==Crystal structure of a nucleoside diphosphate kinase NDK from Helicobacter pylori== | ==Crystal structure of a nucleoside diphosphate kinase NDK from Helicobacter pylori== | ||
<StructureSection load='6ay1' size='340' side='right' caption='[[6ay1]], [[Resolution|resolution]] 2.05Å' scene=''> | <StructureSection load='6ay1' size='340' side='right'caption='[[6ay1]], [[Resolution|resolution]] 2.05Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6ay1]] is a 8 chain structure with sequence from [ | <table><tr><td colspan='2'>[[6ay1]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AY1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AY1 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEZ:HEXANE-1,6-DIOL'>HEZ</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr> | ||
< | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ay1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ay1 OCA], [https://pdbe.org/6ay1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ay1 RCSB], [https://www.ebi.ac.uk/pdbsum/6ay1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ay1 ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/NDK_HELPG NDK_HELPG] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | ||
==See Also== | |||
*[[Nucleoside diphosphate kinase 3D structures|Nucleoside diphosphate kinase 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Helicobacter pylori]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Edwards | [[Category: Edwards TE]] | ||
Latest revision as of 17:28, 4 October 2023
Crystal structure of a nucleoside diphosphate kinase NDK from Helicobacter pyloriCrystal structure of a nucleoside diphosphate kinase NDK from Helicobacter pylori
Structural highlights
FunctionNDK_HELPG Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. See Also |
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