5up0: Difference between revisions

<table><tr><td colspan='2'>[[5up0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UP0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UP0 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.04&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8HP:6-[(4-CHLOROPHENYL)METHYL]-8,9,10,11-TETRAHYDRO[1]BENZOTHIENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5(6H)-ONE'>8HP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5up0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5up0 OCA], [https://pdbe.org/5up0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5up0 RCSB], [https://www.ebi.ac.uk/pdbsum/5up0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5up0 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/PDE1B_HUMAN PDE1B_HUMAN] Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a preference for cGMP as a substrate.

[[Category: Homo sapiens]]

[[Category: Aertgeerts K]]

[[Category: Allerston CK]]

[[Category: Barker R]]

[[Category: Cedervall EP]]

[[Category: Sridhar V]]

[[Category: Xu R]]