5tjk: Difference between revisions

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<StructureSection load='5tjk' size='340' side='right'caption='[[5tjk]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
<StructureSection load='5tjk' size='340' side='right'caption='[[5tjk]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5tjk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TJK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TJK FirstGlance]. <br>
<table><tr><td colspan='2'>[[5tjk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TJK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TJK FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGA:alpha-L-Fucp-(1- 2)[alpha-D-GalNAcp-(1- 3)]-beta-D-Galp-O(CH2)7CH3'>BGA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5tjn|5tjn]], [[5tjl|5tjl]], [[5tjm|5tjm]], [[5tjo|5tjo]], [[5tjp|5tjp]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HSH:OCTYL+BETA-D-GALACTOPYRANOSIDE'>HSH</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ABO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tjk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tjk OCA], [https://pdbe.org/5tjk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tjk RCSB], [https://www.ebi.ac.uk/pdbsum/5tjk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tjk ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tjk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tjk OCA], [http://pdbe.org/5tjk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tjk RCSB], [http://www.ebi.ac.uk/pdbsum/5tjk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tjk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN]] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.  
[https://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Evans, S V]]
[[Category: Evans SV]]
[[Category: Gagnon, S M.L]]
[[Category: Gagnon SML]]
[[Category: Legg, M S.G]]
[[Category: Legg MSG]]
[[Category: Glycosyltransferase]]
[[Category: Gt-a fold]]
[[Category: Histo blood group enzyme]]
[[Category: Product trisaccharide]]
[[Category: Transferase]]

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