5sup: Difference between revisions

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-==Structure of mRNA export factors==
+==Crystal structure of the Sub2-Yra1 complex in association with RNA==
 <StructureSection load='5sup' size='340' side='right'caption='[[5sup]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[5sup]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SUP OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5SUP FirstGlance]. <br>
+<table><tr><td colspan='2'>[[5sup]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SUP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SUP FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5suq|5suq]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SUB2, YDL084W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast]), YRA1, YDR381W, D9481.2, D9509.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5sup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5sup OCA], [https://pdbe.org/5sup PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5sup RCSB], [https://www.ebi.ac.uk/pdbsum/5sup PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5sup ProSAT]</span></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA_helicase RNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.13 3.6.4.13] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5sup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5sup OCA], [http://pdbe.org/5sup PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5sup RCSB], [http://www.ebi.ac.uk/pdbsum/5sup PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5sup ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/SUB2_YEAST SUB2_YEAST]] ATP-binding RNA helicase component of the TREX complex involved in transcription elongation and required for the export of mRNA out of the nucleus. SUB2 plays also a role in pre-mRNA splicing and spliceosome assembly. May be involved in rDNA and telomeric silencing, and maintenance of genome integrity.<ref>PMID:10077188</ref> <ref>PMID:11156602</ref> <ref>PMID:11156603</ref> <ref>PMID:11156604</ref> <ref>PMID:11463828</ref> <ref>PMID:11675790</ref> <ref>PMID:11696331</ref> <ref>PMID:11979277</ref> <ref>PMID:12034490</ref> <ref>PMID:12093753</ref> <ref>PMID:12417727</ref> <ref>PMID:12871933</ref> <ref>PMID:15942929</ref>  [[http://www.uniprot.org/uniprot/YRA1_YEAST YRA1_YEAST]] RNA-binding RNA annealing protein. May have a role in pre-mRNA metabolism. Component the TREX complex, which operates in coupling transcription elongation to mRNA export.<ref>PMID:15584090</ref>
+[https://www.uniprot.org/uniprot/YRA1_YEAST YRA1_YEAST] RNA-binding RNA annealing protein. May have a role in pre-mRNA metabolism. Component the TREX complex, which operates in coupling transcription elongation to mRNA export.<ref>PMID:15584090</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 28: / Line 26: @@
 __TOC__
 </StructureSection>
-[[Category: Baker's yeast]]
 [[Category: Large Structures]]
-[[Category: RNA helicase]]
+[[Category: Saccharomyces cerevisiae S288C]]
-[[Category: Blobel, G]]
+[[Category: Synthetic construct]]
-[[Category: Ren, Y]]
+[[Category: Blobel G]]
-[[Category: Schmiege, P]]
+[[Category: Ren Y]]
-[[Category: Hydrolase-rna complex]]
+[[Category: Schmiege P]]
-[[Category: Mrna export]]