5bo3: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5bo3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Ra Mycobacterium tuberculosis H37Ra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BO3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BO3 FirstGlance]. <br> | <table><tr><td colspan='2'>[[5bo3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Ra Mycobacterium tuberculosis H37Ra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BO3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BO3 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7P2:2-[(2-CARBOXYPHENYL)AMINO]-5-(4-PHOSPHONOBUTOXY)BENZOIC+ACID'>7P2</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7P2:2-[(2-CARBOXYPHENYL)AMINO]-5-(4-PHOSPHONOBUTOXY)BENZOIC+ACID'>7P2</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bo3 OCA], [https://pdbe.org/5bo3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bo3 RCSB], [https://www.ebi.ac.uk/pdbsum/5bo3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bo3 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bo3 OCA], [https://pdbe.org/5bo3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bo3 RCSB], [https://www.ebi.ac.uk/pdbsum/5bo3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bo3 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
Latest revision as of 11:28, 27 September 2023
Bianthranilate-like inhibitor with 5 atom "line" and phosphonate "hook" fishing for hydrogen bond donors in Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)Bianthranilate-like inhibitor with 5 atom "line" and phosphonate "hook" fishing for hydrogen bond donors in Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
Structural highlights
FunctionTRPD_MYCTA Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA). See Also |
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