5k1h: Difference between revisions

<table><tr><td colspan='2'>[[5k1h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K1H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5K1H FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.9&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5k1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k1h OCA], [https://pdbe.org/5k1h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5k1h RCSB], [https://www.ebi.ac.uk/pdbsum/5k1h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5k1h ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/EIF3B_HUMAN EIF3B_HUMAN] Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.<ref>PMID:9388245</ref>  

[[Category: Homo sapiens]]

[[Category: Oryctolagus cuniculus]]

[[Category: Brito Querido J]]

[[Category: Hashem Y]]

[[Category: Kuhn L]]

[[Category: Mancera-Martinez E]]

[[Category: Myasnikov AG]]

[[Category: Renaud A]]

[[Category: Simonetti A]]