7cei: Difference between revisions

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OCA

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 ==THE ENDONUCLEASE DOMAIN OF COLICIN E7 IN COMPLEX WITH ITS INHIBITOR IM7 PROTEIN==
-<StructureSection load='7cei' size='340' side='right' caption='[[7cei]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
+<StructureSection load='7cei' size='340' side='right'caption='[[7cei]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[7cei]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecow3 Ecow3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CEI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=7CEI FirstGlance]. <br>
+<table><tr><td colspan='2'>[[7cei]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_str._K-12_substr._W3110 Escherichia coli str. K-12 substr. W3110]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CEI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CEI FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CEIE7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=316407 ECOW3])</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=7cei FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cei OCA], [http://pdbe.org/7cei PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7cei RCSB], [http://www.ebi.ac.uk/pdbsum/7cei PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cei FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cei OCA], [https://pdbe.org/7cei PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cei RCSB], [https://www.ebi.ac.uk/pdbsum/7cei PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cei ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/IMM7_ECOLX IMM7_ECOLX]] This protein is able to protect a cell, which harbors the plasmid ColE7 encoding colicin E7, against colicin E7, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity. Dimeric ImmE7 may possess a RNase activity that cleaves its own mRNA at a specific site and thus autoregulates translational expression of the downstream ceiE7 gene as well as degradation of the upstream ceaE7 mRNA. [[http://www.uniprot.org/uniprot/CEA7_ECOLX CEA7_ECOLX]] This plasmid-coded bactericidal protein is an endonuclease active on both single- and double-stranded DNA but with undefined specificity.  Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria.
+[https://www.uniprot.org/uniprot/IMM7_ECOLX IMM7_ECOLX] This protein is able to protect a cell, which harbors the plasmid ColE7 encoding colicin E7, against colicin E7, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity. Dimeric ImmE7 may possess a RNase activity that cleaves its own mRNA at a specific site and thus autoregulates translational expression of the downstream ceiE7 gene as well as degradation of the upstream ceaE7 mRNA.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ce/7cei_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ce/7cei_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
@@ Line 30: / Line 31: @@
 ==See Also==
-*[[Colicin|Colicin]]
+*[[Colicin 3D structures|Colicin 3D structures]]
 *[[Colicin Immunity Protein|Colicin Immunity Protein]]
-*[[Colicin Immunity Protein 7|Colicin Immunity Protein 7]]
+*[[Colicin immunity protein 3D structures|Colicin immunity protein 3D structures]]
-*[[Colicin Immunity Protein 9|Colicin Immunity Protein 9]]
-*[[Directed evolution|Directed evolution]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Ecow3]]
+[[Category: Escherichia coli str. K-12 substr. W3110]]
-[[Category: Chak, K F]]
+[[Category: Large Structures]]
-[[Category: Ko, T P]]
+[[Category: Chak KF]]
-[[Category: Ku, W Y]]
+[[Category: Ko TP]]
-[[Category: Liao, C C]]
+[[Category: Ku WY]]
-[[Category: Yuan, H S]]
+[[Category: Liao CC]]
-[[Category: Dnase]]
+[[Category: Yuan HS]]
-[[Category: E-group colicin]]
-[[Category: Immune system]]
-[[Category: Protein recognition]]
-[[Category: Protein-protein interaction]]