4mya: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4mya]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis_str._Ames Bacillus anthracis str. Ames]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MYA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MYA FirstGlance]. <br> | <table><tr><td colspan='2'>[[4mya]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis_str._Ames Bacillus anthracis str. Ames]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MYA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MYA FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2EY:4-{(1R)-1-[1-(4-CHLOROPHENYL)-1H-1,2,3-TRIAZOL-4-YL]ETHOXY}QUINOLIN-2(1H)-ONE'>2EY</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8997Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2EY:4-{(1R)-1-[1-(4-CHLOROPHENYL)-1H-1,2,3-TRIAZOL-4-YL]ETHOXY}QUINOLIN-2(1H)-ONE'>2EY</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mya OCA], [https://pdbe.org/4mya PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mya RCSB], [https://www.ebi.ac.uk/pdbsum/4mya PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mya ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mya OCA], [https://pdbe.org/4mya PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mya RCSB], [https://www.ebi.ac.uk/pdbsum/4mya PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mya ProSAT]</span></td></tr> | ||
</table> | </table> | ||
Latest revision as of 19:44, 20 September 2023
Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase with an Internal Deletion of the CBS Domain from Bacillus anthracis str. Ames complexed with inhibitor A110Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase with an Internal Deletion of the CBS Domain from Bacillus anthracis str. Ames complexed with inhibitor A110
Structural highlights
FunctionA0A6L8P2U9_BACAN Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964] See Also |
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