3n2g: Difference between revisions

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 ==TUBULIN-NSC 613863: RB3 Stathmin-like domain complex==
-<StructureSection load='3n2g' size='340' side='right' caption='[[3n2g]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
+<StructureSection load='3n2g' size='340' side='right'caption='[[3n2g]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3n2g]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat] and [http://en.wikipedia.org/wiki/Ovis_aries Ovis aries]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N2G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N2G FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3n2g]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Ovis_aries Ovis aries] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N2G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N2G FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=G2N:ETHYL+[(2R)-5-AMINO-2-METHYL-3-PHENYL-1,2-DIHYDROPYRIDO[3,4-B]PYRAZIN-7-YL]CARBAMATE'>G2N</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3n2k|3n2k]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G2N:ETHYL+[(2R)-5-AMINO-2-METHYL-3-PHENYL-1,2-DIHYDROPYRIDO[3,4-B]PYRAZIN-7-YL]CARBAMATE'>G2N</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Stmn4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n2g OCA], [https://pdbe.org/3n2g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n2g RCSB], [https://www.ebi.ac.uk/pdbsum/3n2g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n2g ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n2g OCA], [http://pdbe.org/3n2g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3n2g RCSB], [http://www.ebi.ac.uk/pdbsum/3n2g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3n2g ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/D0VWZ0_SHEEP D0VWZ0_SHEEP]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity).[RuleBase:RU003505][SAAS:SAAS023123_004_019801] [[http://www.uniprot.org/uniprot/STMN4_RAT STMN4_RAT]] Exhibits microtubule-destabilizing activity.<ref>PMID:15039434</ref> <ref>PMID:12111843</ref> <ref>PMID:15014504</ref>  [[http://www.uniprot.org/uniprot/D0VWY9_SHEEP D0VWY9_SHEEP]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity).[RuleBase:RU003505]
+[https://www.uniprot.org/uniprot/D0VWZ0_SHEEP D0VWZ0_SHEEP] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity).[RuleBase:RU003505][SAAS:SAAS023123_004_019801]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 32: / Line 31: @@
 ==See Also==
-*[[Stathmin|Stathmin]]
+*[[Stathmin-4 3D structures|Stathmin-4 3D structures]]
-*[[Tubulin|Tubulin]]
+*[[Tubulin 3D Structures|Tubulin 3D Structures]]
-*[[User:Alisa Cario|User:Alisa Cario]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Buffalo rat]]
+[[Category: Large Structures]]
 [[Category: Ovis aries]]
-[[Category: Alfonso, C]]
+[[Category: Rattus norvegicus]]
-[[Category: Allegro, D]]
+[[Category: Alfonso C]]
-[[Category: Andreu, J M]]
+[[Category: Allegro D]]
-[[Category: Barbier, P]]
+[[Category: Andreu JM]]
-[[Category: Devred, F]]
+[[Category: Barbier P]]
-[[Category: Dorleans, A]]
+[[Category: Devred F]]
-[[Category: Knossow, M]]
+[[Category: Dorleans A]]
-[[Category: Peyrot, V]]
+[[Category: Knossow M]]
-[[Category: Sanz, L]]
+[[Category: Peyrot V]]
-[[Category: Alpha-tubulin]]
+[[Category: Sanz L]]
-[[Category: Beta-tubulin]]
-[[Category: Cell cycle]]
-[[Category: Colchicine domain]]
-[[Category: Microtubule]]
-[[Category: Stathmin]]
-[[Category: Tubulin]]