3lzd: Difference between revisions
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<StructureSection load='3lzd' size='340' side='right'caption='[[3lzd]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='3lzd' size='340' side='right'caption='[[3lzd]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3lzd]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3lzd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LZD FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lzd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lzd OCA], [https://pdbe.org/3lzd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lzd RCSB], [https://www.ebi.ac.uk/pdbsum/3lzd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lzd ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/DPH2_PYRHO DPH2_PYRHO] Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).<ref>PMID:20559380</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Dzikovski | [[Category: Pyrococcus horikoshii]] | ||
[[Category: Ealick | [[Category: Dzikovski B]] | ||
[[Category: Freed | [[Category: Ealick SE]] | ||
[[Category: Koralewski | [[Category: Freed J]] | ||
[[Category: Krebs | [[Category: Koralewski RM]] | ||
[[Category: Lee | [[Category: Krebs C]] | ||
[[Category: Lin | [[Category: Lee M]] | ||
[[Category: Torelli | [[Category: Lin H]] | ||
[[Category: Wang | [[Category: Torelli AT]] | ||
[[Category: Zhang | [[Category: Wang E]] | ||
[[Category: Zhu | [[Category: Zhang Y]] | ||
[[Category: Zhu X]] | |||