3js4: Difference between revisions

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==Crystal structure of iron superoxide dismutase from Anaplasma phagocytophilum==
==Crystal structure of iron superoxide dismutase from Anaplasma phagocytophilum==
<StructureSection load='3js4' size='340' side='right' caption='[[3js4]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='3js4' size='340' side='right'caption='[[3js4]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3js4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Anapz Anapz]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JS4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JS4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3js4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Anaplasma_phagocytophilum_str._HZ Anaplasma phagocytophilum str. HZ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JS4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JS4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">sodB, APH_0371 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=212042 ANAPZ])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3js4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3js4 OCA], [https://pdbe.org/3js4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3js4 RCSB], [https://www.ebi.ac.uk/pdbsum/3js4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3js4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3js4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3js4 OCA], [http://pdbe.org/3js4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3js4 RCSB], [http://www.ebi.ac.uk/pdbsum/3js4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3js4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/Q2GKX4_ANAPZ Q2GKX4_ANAPZ]] Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity).  
[https://www.uniprot.org/uniprot/Q2GKX4_ANAPZ Q2GKX4_ANAPZ] Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/js/3js4_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/js/3js4_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3js4 ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3js4 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Anapz]]
[[Category: Anaplasma phagocytophilum str. HZ]]
[[Category: Superoxide dismutase]]
[[Category: Large Structures]]
[[Category: Structural genomic]]
[[Category: Fe]]
[[Category: Gram-negative bacteria]]
[[Category: Human granulocytic anaplasmosis]]
[[Category: Metalloenzyme]]
[[Category: Niaid]]
[[Category: Oxidoreductase]]
[[Category: Ssgcid]]

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