5ir4: Difference between revisions

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<StructureSection load='5ir4' size='340' side='right'caption='[[5ir4]], [[Resolution|resolution]] 1.48&Aring;' scene=''>
<StructureSection load='5ir4' size='340' side='right'caption='[[5ir4]], [[Resolution|resolution]] 1.48&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ir4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IR4 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5IR4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ir4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IR4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IR4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=ZPE:(2R)-3-{[(S)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-2-(TETRADEC-5-ENOYLOXY)PROPYL+(11Z)-OCTADEC-11-ENOATE'>ZPE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.48&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ir5|5ir5]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=ZPE:(2R)-3-{[(S)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-2-(TETRADEC-5-ENOYLOXY)PROPYL+(11Z)-OCTADEC-11-ENOATE'>ZPE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ir4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ir4 OCA], [http://pdbe.org/5ir4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ir4 RCSB], [http://www.ebi.ac.uk/pdbsum/5ir4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ir4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ir4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ir4 OCA], [https://pdbe.org/5ir4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ir4 RCSB], [https://www.ebi.ac.uk/pdbsum/5ir4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ir4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LOXA_PSEAE LOXA_PSEAE] Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid (HpETE) which is rapidly reduced to hydroxyeicosatetraenoic acid (HETE). Could act on exogenous human-derived substrates to potentially modulate the local inflammatory responses during P.aeruginosa infections.<ref>PMID:14766977</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Banthiya, S]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Kalms, J]]
[[Category: Banthiya S]]
[[Category: Kuhn, H]]
[[Category: Galemou Yoga E]]
[[Category: Scheerer, P]]
[[Category: Kalms J]]
[[Category: Yoga, E Galemou]]
[[Category: Kuhn H]]
[[Category: Eicosanoid]]
[[Category: Scheerer P]]
[[Category: Infectious disease]]
[[Category: Non-heme iron enzyme]]
[[Category: Oxidoreductase]]
[[Category: Protein-phospholipid complex]]

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