5ipq: Difference between revisions

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OCA

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 <SX load='5ipq' size='340' side='right' viewer='molstar' caption='[[5ipq]], [[Resolution|resolution]] 13.50&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[5ipq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/African_clawed_frog African clawed frog]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IPQ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5IPQ FirstGlance]. <br>
+<table><tr><td colspan='2'>[[5ipq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IPQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IPQ FirstGlance]. <br>
-</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5iou|5iou]], [[5iov|5iov]], [[5ips|5ips]], [[5ipr|5ipr]], [[5ipt|5ipt]], [[5ipu|5ipu]], [[5ipv|5ipv]]</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 13.5&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NR2B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=8355 African clawed frog])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ipq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ipq OCA], [https://pdbe.org/5ipq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ipq RCSB], [https://www.ebi.ac.uk/pdbsum/5ipq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ipq ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ipq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ipq OCA], [http://pdbe.org/5ipq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ipq RCSB], [http://www.ebi.ac.uk/pdbsum/5ipq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ipq ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/NMDZ1_XENLA NMDZ1_XENLA] Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+) (PubMed:16214956, PubMed:19524674, PubMed:21677647, PubMed:25008524, PubMed:26912815, PubMed:27135925, Ref.11, PubMed:28232581). Sensitivity to glutamate and channel kinetics depend on the subunit composition (Probable).<ref>PMID:16214956</ref> <ref>PMID:19524674</ref> <ref>PMID:21677647</ref> <ref>PMID:25008524</ref> <ref>PMID:26912815</ref> <ref>PMID:27135925</ref> <ref>PMID:28232581</ref> [PDB:5IOV]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 24: / Line 25: @@
 __TOC__
 </SX>
-[[Category: African clawed frog]]
 [[Category: Large Structures]]
-[[Category: Goehring, A]]
+[[Category: Xenopus laevis]]
-[[Category: Gouaux, E]]
+[[Category: Goehring A]]
-[[Category: Lee, C H]]
+[[Category: Gouaux E]]
-[[Category: Mchaourab, S H]]
+[[Category: Lee CH]]
-[[Category: Stein, A R]]
+[[Category: Mchaourab SH]]
-[[Category: Yoshioka, C]]
+[[Category: Stein AR]]
-[[Category: Zhu, S]]
+[[Category: Yoshioka C]]
-[[Category: Ligand-gated ion channel]]
+[[Category: Zhu S]]
-[[Category: Signaling protein]]
-[[Category: Synaptic transmission]]