3dbf: Difference between revisions

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<StructureSection load='3dbf' size='340' side='right'caption='[[3dbf]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
<StructureSection load='3dbf' size='340' side='right'caption='[[3dbf]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3dbf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Brachidanio_rerio Brachidanio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DBF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DBF FirstGlance]. <br>
<table><tr><td colspan='2'>[[3dbf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DBF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DBF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5FR:4-({1-[3-(3-AMINO-3-OXOPROPYL)-5-CHLOROPHENYL]-3-METHYL-1H-PYRAZOLO[4,3-C]PYRIDIN-6-YL}AMINO)-3-METHOXY-N-(1-METHYLPIPERIDIN-4-YL)BENZAMIDE'>5FR</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3d5w|3d5w]], [[3db6|3db6]], [[3db8|3db8]], [[3dbc|3dbc]], [[3dbd|3dbd]], [[3dbe|3dbe]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5FR:4-({1-[3-(3-AMINO-3-OXOPROPYL)-5-CHLOROPHENYL]-3-METHYL-1H-PYRAZOLO[4,3-C]PYRIDIN-6-YL}AMINO)-3-METHOXY-N-(1-METHYLPIPERIDIN-4-YL)BENZAMIDE'>5FR</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">plk1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7955 Brachidanio rerio])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Polo_kinase Polo kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.21 2.7.11.21] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dbf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dbf OCA], [https://pdbe.org/3dbf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dbf RCSB], [https://www.ebi.ac.uk/pdbsum/3dbf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dbf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dbf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dbf OCA], [https://pdbe.org/3dbf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dbf RCSB], [https://www.ebi.ac.uk/pdbsum/3dbf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dbf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q4KMI8_DANRE Q4KMI8_DANRE]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Brachidanio rerio]]
[[Category: Danio rerio]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Polo kinase]]
[[Category: Barr KJ]]
[[Category: Barr, K J]]
[[Category: Elling RA]]
[[Category: Elling, R A]]
[[Category: Romanowski MJ]]
[[Category: Romanowski, M J]]
[[Category: Zhu J]]
[[Category: Zhu, J]]
[[Category: Catalytic domain]]
[[Category: Kinase]]
[[Category: Plk1]]
[[Category: Polo-like kinase 1]]
[[Category: Small-molecule inhibitor]]
[[Category: Transferase]]

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