2pdl: Difference between revisions

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<StructureSection load='2pdl' size='340' side='right'caption='[[2pdl]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
<StructureSection load='2pdl' size='340' side='right'caption='[[2pdl]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2pdl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PDL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PDL FirstGlance]. <br>
<table><tr><td colspan='2'>[[2pdl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PDL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PDL FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=TOL:TOLRESTAT'>TOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.47&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ah3|1ah3]], [[2fzd|2fzd]], [[2fzb|2fzb]], [[2pd5|2pd5]], [[2pd9|2pd9]], [[2pdb|2pdb]], [[2pdc|2pdc]], [[2pdf|2pdf]], [[2pdg|2pdg]], [[2pdh|2pdh]], [[2pdi|2pdi]], [[2pdj|2pdj]], [[2pdk|2pdk]], [[2pdm|2pdm]], [[2pdn|2pdn]], [[2pdp|2pdp]], [[2pdq|2pdq]], [[2pdu|2pdu]], [[2pdw|2pdw]], [[2pdx|2pdx]], [[2pdy|2pdy]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=TOL:TOLRESTAT'>TOL</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ALR2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pdl OCA], [https://pdbe.org/2pdl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pdl RCSB], [https://www.ebi.ac.uk/pdbsum/2pdl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pdl ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pdl OCA], [https://pdbe.org/2pdl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pdl RCSB], [https://www.ebi.ac.uk/pdbsum/2pdl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pdl ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN]] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.  
[https://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aldehyde reductase]]
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Heine, A]]
[[Category: Heine A]]
[[Category: Klebe, G]]
[[Category: Klebe G]]
[[Category: Steuber, H]]
[[Category: Steuber H]]
[[Category: Oxidoreductase]]
[[Category: Tim barrel]]

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