2i0d: Difference between revisions

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<StructureSection load='2i0d' size='340' side='right'caption='[[2i0d]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='2i0d' size='340' side='right'caption='[[2i0d]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2i0d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I0D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I0D FirstGlance]. <br>
<table><tr><td colspan='2'>[[2i0d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I0D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I0D FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MUT:(5S)-3-(3-ACETYLPHENYL)-N-[(1S,2R)-1-BENZYL-2-HYDROXY-3-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}PROPYL]-2-OXO-1,3-OXAZOLIDINE-5-CARBOXAMIDE'>MUT</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ioa|2ioa]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MUT:(5S)-3-(3-ACETYLPHENYL)-N-[(1S,2R)-1-BENZYL-2-HYDROXY-3-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}PROPYL]-2-OXO-1,3-OXAZOLIDINE-5-CARBOXAMIDE'>MUT</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pol ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i0d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i0d OCA], [https://pdbe.org/2i0d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i0d RCSB], [https://www.ebi.ac.uk/pdbsum/2i0d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i0d ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i0d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i0d OCA], [https://pdbe.org/2i0d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i0d RCSB], [https://www.ebi.ac.uk/pdbsum/2i0d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i0d ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/O38731_9HIV1 O38731_9HIV1]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human immunodeficiency virus 1]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Ali, A]]
[[Category: Ali A]]
[[Category: Anjum, S G]]
[[Category: Anjum SG]]
[[Category: Cao, H]]
[[Category: Cao H]]
[[Category: Nalam, M N.L]]
[[Category: Nalam MNL]]
[[Category: Rana, T M]]
[[Category: Rana TM]]
[[Category: Reddy, K K]]
[[Category: Reddy KK]]
[[Category: Schiffer, C A]]
[[Category: Schiffer CA]]
[[Category: Drug design]]
[[Category: Hiv-1 protease]]
[[Category: Hydrolase]]
[[Category: Protease inhibitor]]

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