2gf0: Difference between revisions

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<StructureSection load='2gf0' size='340' side='right'caption='[[2gf0]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='2gf0' size='340' side='right'caption='[[2gf0]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2gf0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GF0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2gf0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GF0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DIRAS1, GBTS1, RIG ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gf0 OCA], [https://pdbe.org/2gf0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gf0 RCSB], [https://www.ebi.ac.uk/pdbsum/2gf0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gf0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gf0 OCA], [https://pdbe.org/2gf0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gf0 RCSB], [https://www.ebi.ac.uk/pdbsum/2gf0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gf0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/DIRA1_HUMAN DIRA1_HUMAN]] Displays low GTPase activity and exist predominantly in the GTP-bound form.  
[https://www.uniprot.org/uniprot/DIRA1_HUMAN DIRA1_HUMAN] Displays low GTPase activity and exist predominantly in the GTP-bound form.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C]]
[[Category: Arrowsmith C]]
[[Category: Bray, J]]
[[Category: Bray J]]
[[Category: Delft, F von]]
[[Category: Doyle D]]
[[Category: Doyle, D]]
[[Category: Edwards A]]
[[Category: Edwards, A]]
[[Category: Elkins J]]
[[Category: Elkins, J]]
[[Category: Fedorov O]]
[[Category: Fedorov, O]]
[[Category: Gileadi O]]
[[Category: Gileadi, O]]
[[Category: Niesen FE]]
[[Category: Niesen, F E]]
[[Category: Papagrigoriou E]]
[[Category: Papagrigoriou, E]]
[[Category: Salah E]]
[[Category: Structural genomic]]
[[Category: Schoch G]]
[[Category: Salah, E]]
[[Category: Sundstrom M]]
[[Category: Schoch, G]]
[[Category: Turnbull AP]]
[[Category: Sundstrom, M]]
[[Category: Weigelt J]]
[[Category: Turnbull, A P]]
[[Category: Wen-Hwa L]]
[[Category: Weigelt, J]]
[[Category: Yang X]]
[[Category: Wen-Hwa, L]]
[[Category: Von Delft F]]
[[Category: Yang, X]]
[[Category: Dira]]
[[Category: Gdp/gtp binding]]
[[Category: Gtp hydrolysis]]
[[Category: Sgc]]
[[Category: Transport protein]]

Latest revision as of 12:39, 30 August 2023

The crystal structure of the human DiRas1 GTPase in the inactive GDP bound stateThe crystal structure of the human DiRas1 GTPase in the inactive GDP bound state

Structural highlights

2gf0 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DIRA1_HUMAN Displays low GTPase activity and exist predominantly in the GTP-bound form.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2gf0, resolution 1.90Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA