2y68: Difference between revisions

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<StructureSection load='2y68' size='340' side='right'caption='[[2y68]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
<StructureSection load='2y68' size='340' side='right'caption='[[2y68]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2y68]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y68 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y68 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2y68]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y68 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y68 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=T04:2-[[2-FLUORO-5-[[[4-[(Z)-(4-OXO-2-SULFANYLIDENE-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]PHENYL]AMINO]METHYL]PHENYL]CARBONYLAMINO]PENTANEDIOIC+ACID'>T04</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.49&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=T04:2-[[2-FLUORO-5-[[[4-[(Z)-(4-OXO-2-SULFANYLIDENE-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]PHENYL]AMINO]METHYL]PHENYL]CARBONYLAMINO]PENTANEDIOIC+ACID'>T04</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2uuo|2uuo]], [[2jfg|2jfg]], [[4uag|4uag]], [[2uag|2uag]], [[3uag|3uag]], [[1e0d|1e0d]], [[2x5o|2x5o]], [[1eeh|1eeh]], [[2jff|2jff]], [[2vte|2vte]], [[2wjp|2wjp]], [[2vtd|2vtd]], [[2y1o|2y1o]], [[1uag|1uag]], [[2jfh|2jfh]], [[2uup|2uup]], [[2y66|2y66]], [[2y67|2y67]]</div></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/UDP-N-acetylmuramoyl-L-alanine--D-glutamate_ligase UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.9 6.3.2.9] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y68 OCA], [https://pdbe.org/2y68 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y68 RCSB], [https://www.ebi.ac.uk/pdbsum/2y68 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y68 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y68 OCA], [https://pdbe.org/2y68 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y68 RCSB], [https://www.ebi.ac.uk/pdbsum/2y68 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y68 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/MURD_ECOLI MURD_ECOLI]] Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).[HAMAP-Rule:MF_00639]  
[https://www.uniprot.org/uniprot/MURD_ECOLI MURD_ECOLI] Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).[HAMAP-Rule:MF_00639]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase]]
[[Category: Blanot D]]
[[Category: Blanot, D]]
[[Category: Contreras-Martel C]]
[[Category: Contreras-Martel, C]]
[[Category: Dessen A]]
[[Category: Dessen, A]]
[[Category: Gobec S]]
[[Category: Gobec, S]]
[[Category: Kikelj D]]
[[Category: Kikelj, D]]
[[Category: Kovac A]]
[[Category: Kovac, A]]
[[Category: Muller-Premru M]]
[[Category: Muller-Premru, M]]
[[Category: Patin D]]
[[Category: Patin, D]]
[[Category: Peterlin-Masic L]]
[[Category: Peterlin-Masic, L]]
[[Category: Sink R]]
[[Category: Sink, R]]
[[Category: Tomasic T]]
[[Category: Tomasic, T]]
[[Category: Zega A]]
[[Category: Zega, A]]
[[Category: Zidar N]]
[[Category: Zidar, N]]
[[Category: Atp-binding]]
[[Category: Cell cycle]]
[[Category: Cell division]]
[[Category: Cell shape]]
[[Category: Cell wall]]
[[Category: Cell wall biogenesis/degradation]]
[[Category: Ligase]]
[[Category: Nucleotide-binding]]
[[Category: Peptidoglycan synthesis]]
[[Category: Uma]]

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