5huy: Difference between revisions

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 <StructureSection load='5huy' size='340' side='right'caption='[[5huy]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[5huy]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Hcmvo Hcmvo] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HUY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HUY FirstGlance]. <br>
+<table><tr><td colspan='2'>[[5huy]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_herpesvirus_5_strain_Toledo Human herpesvirus 5 strain Toledo] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HUY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HUY FirstGlance]. <br>
-</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3q5u|3q5u]], [[5huw|5huw]]</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.979&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Kpna2, Rch1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5huy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5huy OCA], [https://pdbe.org/5huy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5huy RCSB], [https://www.ebi.ac.uk/pdbsum/5huy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5huy ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5huy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5huy OCA], [http://pdbe.org/5huy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5huy RCSB], [http://www.ebi.ac.uk/pdbsum/5huy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5huy ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/IMA1_MOUSE IMA1_MOUSE]] Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
+[https://www.uniprot.org/uniprot/IMA1_MOUSE IMA1_MOUSE] Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
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 __TOC__
 </StructureSection>
-[[Category: Hcmvo]]
+[[Category: Human herpesvirus 5 strain Toledo]]
 [[Category: Large Structures]]
-[[Category: Lk3 transgenic mice]]
+[[Category: Mus musculus]]
-[[Category: Cingolani, G]]
+[[Category: Cingolani G]]
-[[Category: Lokareddy, R K]]
+[[Category: Lokareddy RK]]
-[[Category: Sankhala, R S]]
+[[Category: Sankhala RS]]
-[[Category: Hcmv small terminase]]
-[[Category: Importin alpha-1]]
-[[Category: Nl]]
-[[Category: Nuclear import]]
-[[Category: Transport protein-viral protein complex]]
-[[Category: Viral protein]]