1p3b: Difference between revisions
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<StructureSection load='1p3b' size='340' side='right'caption='[[1p3b]], [[Resolution|resolution]] 3.00Å' scene=''> | <StructureSection load='1p3b' size='340' side='right'caption='[[1p3b]], [[Resolution|resolution]] 3.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1p3b]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/ ] and [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1p3b]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P3B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P3B FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p3b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p3b OCA], [https://pdbe.org/1p3b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p3b RCSB], [https://www.ebi.ac.uk/pdbsum/1p3b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p3b ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p3b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p3b OCA], [https://pdbe.org/1p3b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p3b RCSB], [https://www.ebi.ac.uk/pdbsum/1p3b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p3b ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/H4_XENLA H4_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Bao | [[Category: Xenopus laevis]] | ||
[[Category: Dyer | [[Category: Bao Y]] | ||
[[Category: Edayathumangalam | [[Category: Dyer PN]] | ||
[[Category: Forsberg | [[Category: Edayathumangalam RS]] | ||
[[Category: Luger | [[Category: Forsberg LJ]] | ||
[[Category: Muthurajan | [[Category: Luger K]] | ||
[[Category: White | [[Category: Muthurajan UM]] | ||
[[Category: White CL]] | |||