1p3b: Difference between revisions

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<StructureSection load='1p3b' size='340' side='right'caption='[[1p3b]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='1p3b' size='340' side='right'caption='[[1p3b]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1p3b]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/ ] and [https://en.wikipedia.org/wiki/African_clawed_frog African clawed frog]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P3B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P3B FirstGlance]. <br>
<table><tr><td colspan='2'>[[1p3b]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P3B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P3B FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1aoi|1aoi]], [[1f66|1f66]], [[1id3|1id3]], [[1kx3|1kx3]], [[1kx4|1kx4]], [[1kx5|1kx5]], [[1p34|1p34]], [[1p3a|1p3a]], [[1p3f|1p3f]], [[1p3g|1p3g]], [[1p3i|1p3i]], [[1p3k|1p3k]], [[1p3l|1p3l]], [[1p3m|1p3m]], [[1p3o|1p3o]], [[1p3p|1p3p]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p3b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p3b OCA], [https://pdbe.org/1p3b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p3b RCSB], [https://www.ebi.ac.uk/pdbsum/1p3b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p3b ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p3b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p3b OCA], [https://pdbe.org/1p3b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p3b RCSB], [https://www.ebi.ac.uk/pdbsum/1p3b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p3b ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/H4_XENLA H4_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [[https://www.uniprot.org/uniprot/H2B11_XENLA H2B11_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.  
[https://www.uniprot.org/uniprot/H4_XENLA H4_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: African clawed frog]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bao, Y]]
[[Category: Xenopus laevis]]
[[Category: Dyer, P N]]
[[Category: Bao Y]]
[[Category: Edayathumangalam, R S]]
[[Category: Dyer PN]]
[[Category: Forsberg, L J]]
[[Category: Edayathumangalam RS]]
[[Category: Luger, K]]
[[Category: Forsberg LJ]]
[[Category: Muthurajan, U M]]
[[Category: Luger K]]
[[Category: White, C L]]
[[Category: Muthurajan UM]]
[[Category: Chromatin]]
[[Category: White CL]]
[[Category: Nucleosome core particle]]
[[Category: Protein/dna interaction]]
[[Category: Sin mutant]]
[[Category: Structural protein-dna complex]]

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