1n9b: Difference between revisions

No edit summary
No edit summary
Line 3: Line 3:
<StructureSection load='1n9b' size='340' side='right'caption='[[1n9b]], [[Resolution|resolution]] 0.90&Aring;' scene=''>
<StructureSection load='1n9b' size='340' side='right'caption='[[1n9b]], [[Resolution|resolution]] 0.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1n9b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N9B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N9B FirstGlance]. <br>
<table><tr><td colspan='2'>[[1n9b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N9B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N9B FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MA4:CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE'>MA4</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1shv|1shv]], [[1htz|1htz]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MA4:CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE'>MA4</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BLA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 "Bacillus pneumoniae" (Schroeter 1886) Flugge 1886])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n9b OCA], [https://pdbe.org/1n9b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n9b RCSB], [https://www.ebi.ac.uk/pdbsum/1n9b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n9b ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n9b OCA], [https://pdbe.org/1n9b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n9b RCSB], [https://www.ebi.ac.uk/pdbsum/1n9b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n9b ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/BLA3_KLEPN BLA3_KLEPN]] This enzyme hydrolyzes cefotaxime, ceftazidime and other broad spectrum cephalosporins.  
[https://www.uniprot.org/uniprot/BLA3_KLEPN BLA3_KLEPN] This enzyme hydrolyzes cefotaxime, ceftazidime and other broad spectrum cephalosporins.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 38: Line 36:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Beta-lactamase]]
[[Category: Klebsiella pneumoniae]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bonomo, R A]]
[[Category: Bonomo RA]]
[[Category: Hujer, A M]]
[[Category: Hujer AM]]
[[Category: Knox, J R]]
[[Category: Knox JR]]
[[Category: Mayama, K]]
[[Category: Mayama K]]
[[Category: Nukaga, M]]
[[Category: Nukaga M]]
[[Category: Beta-lactam hydrolase]]
[[Category: Detergent binding]]
[[Category: Drug design]]
[[Category: Hydrolase]]
[[Category: Penicillinase]]
[[Category: Radiation damage]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA