1ld3: Difference between revisions

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<StructureSection load='1ld3' size='340' side='right'caption='[[1ld3]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='1ld3' size='340' side='right'caption='[[1ld3]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ld3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_globigii"_migula_1900 "bacillus globigii" migula 1900]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LD3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LD3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ld3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LD3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LD3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1doz|1doz]], [[1c1h|1c1h]], [[1c9e|1c9e]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ferrochelatase Ferrochelatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.1 4.99.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ld3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ld3 OCA], [https://pdbe.org/1ld3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ld3 RCSB], [https://www.ebi.ac.uk/pdbsum/1ld3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ld3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ld3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ld3 OCA], [https://pdbe.org/1ld3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ld3 RCSB], [https://www.ebi.ac.uk/pdbsum/1ld3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ld3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/HEMH_BACSU HEMH_BACSU]] Catalyzes the ferrous insertion into protoporphyrin IX.  
[https://www.uniprot.org/uniprot/CPFC_BACSU CPFC_BACSU] Involved in coproporphyrin-dependent heme b biosynthesis (PubMed:25646457, PubMed:25908396). Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III (PubMed:25646457, PubMed:25908396). It can also insert iron into protoporphyrin IX (PubMed:1459957, PubMed:8119288, PubMed:21052751, PubMed:25646457). Has weaker activity with 2,4 disulfonate, deuteroporphyrin and 2,4 hydroxyethyl (PubMed:25646457, PubMed:12761666). In vitro, can also use Zn(2+) or Cu(2+) (PubMed:8119288, PubMed:16140324, PubMed:21052751, PubMed:12761666).<ref>PMID:12761666</ref> <ref>PMID:1459957</ref> <ref>PMID:16140324</ref> <ref>PMID:21052751</ref> <ref>PMID:25646457</ref> <ref>PMID:25826316</ref> <ref>PMID:25908396</ref> <ref>PMID:8119288</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus globigii migula 1900]]
[[Category: Bacillus subtilis]]
[[Category: Ferrochelatase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Al-Karadaghi, S]]
[[Category: Al-Karadaghi S]]
[[Category: Fodje, M N]]
[[Category: Fodje MN]]
[[Category: Hansson, A]]
[[Category: Hansson A]]
[[Category: Hansson, M]]
[[Category: Hansson M]]
[[Category: Lecerof, D]]
[[Category: Lecerof D]]
[[Category: Leon, R A]]
[[Category: Leon RA]]
[[Category: Olsson, U]]
[[Category: Olsson U]]
[[Category: Ryde, U]]
[[Category: Ryde U]]
[[Category: Sigfridsson, E]]
[[Category: Sigfridsson E]]
[[Category: Lyase]]
[[Category: Pi-helix]]
[[Category: Rossmann fold]]

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