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==Crystal structure of heat shock factor 2-DBD== | ==Crystal structure of heat shock factor 2-DBD== | ||
<StructureSection load='5hdk' size='340' side='right' caption='[[5hdk]], [[Resolution|resolution]] 1.32Å' scene=''> | <StructureSection load='5hdk' size='340' side='right'caption='[[5hdk]], [[Resolution|resolution]] 1.32Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5hdk]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5hdk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HDK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HDK FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.32Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
< | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hdk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hdk OCA], [https://pdbe.org/5hdk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hdk RCSB], [https://www.ebi.ac.uk/pdbsum/5hdk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hdk ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/HSF2_HUMAN HSF2_HUMAN] DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked. | ||
==See Also== | |||
*[[Heat shock factor|Heat shock factor]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Feng H]] | ||
[[Category: | [[Category: Liu W]] | ||
[[Category: | [[Category: Wang DC]] | ||
Latest revision as of 10:32, 9 August 2023
Crystal structure of heat shock factor 2-DBDCrystal structure of heat shock factor 2-DBD
Structural highlights
FunctionHSF2_HUMAN DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked. See Also |
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