1c2u: Difference between revisions
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==SOLUTION STRUCTURE OF [ABU3,35]SHK12-28,17-32== | ==SOLUTION STRUCTURE OF [ABU3,35]SHK12-28,17-32== | ||
<StructureSection load='1c2u' size='340' side='right'caption='[[1c2u | <StructureSection load='1c2u' size='340' side='right'caption='[[1c2u]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1c2u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C2U FirstGlance]. <br> | <table><tr><td colspan='2'>[[1c2u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Stichodactyla_helianthus Stichodactyla helianthus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C2U FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ABA:ALPHA-AMINOBUTYRIC+ACID'>ABA</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c2u OCA], [https://pdbe.org/1c2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c2u RCSB], [https://www.ebi.ac.uk/pdbsum/1c2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c2u ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c2u OCA], [https://pdbe.org/1c2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c2u RCSB], [https://www.ebi.ac.uk/pdbsum/1c2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c2u ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/K1A_STIHL K1A_STIHL] Inhibits voltage-dependent potassium channels. Inhibits Kv1.3/KCNA3 potently and also blocks Kv1.1/KCNA1, Kv1.4/KCNA4, and Kv1.6/KCNA6 at subnanomolar concentrations.<ref>PMID:7660365</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Behm | [[Category: Stichodactyla helianthus]] | ||
[[Category: Chandy | [[Category: Behm D]] | ||
[[Category: Donaldson | [[Category: Chandy KG]] | ||
[[Category: Kalman | [[Category: Donaldson D]] | ||
[[Category: Kem | [[Category: Kalman K]] | ||
[[Category: Lanigan | [[Category: Kem WR]] | ||
[[Category: Manhir | [[Category: Lanigan MD]] | ||
[[Category: McVaugh | [[Category: Manhir VM]] | ||
[[Category: Norton | [[Category: McVaugh CT]] | ||
[[Category: Pennington | [[Category: Norton RS]] | ||
[[Category: Rauer | [[Category: Pennington MW]] | ||
[[Category: Rauer H]] | |||