1tfh: Difference between revisions
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<StructureSection load='1tfh' size='340' side='right'caption='[[1tfh]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='1tfh' size='340' side='right'caption='[[1tfh]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1tfh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1tfh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TFH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TFH FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tfh OCA], [https://pdbe.org/1tfh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tfh RCSB], [https://www.ebi.ac.uk/pdbsum/1tfh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tfh ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tfh OCA], [https://pdbe.org/1tfh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tfh RCSB], [https://www.ebi.ac.uk/pdbsum/1tfh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tfh ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/TF_HUMAN TF_HUMAN] Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.<ref>PMID:12652293</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Edgington | [[Category: Edgington TS]] | ||
[[Category: Huang | [[Category: Huang M]] | ||
[[Category: Ruf | [[Category: Ruf W]] | ||
[[Category: Stefanko | [[Category: Stefanko RS]] | ||
[[Category: Stone | [[Category: Stone MJ]] | ||
[[Category: Stura | [[Category: Stura EA]] | ||
[[Category: Syed | [[Category: Syed R]] | ||
[[Category: Wilson | [[Category: Wilson IA]] | ||